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Novel approach shows promise against UTIs | Center for Women's Infectious Disease Research

Novel approach shows promise against UTIs

New compounds called C-mannosides have been shown to prevent these bacteria from attaching to the bladder wall, a potentially novel way to fight urinary tract infections.

Scientists at Washington University School of Medicine in St. Louis have designed small molecules that prevent bacteria from sticking to the wall of the bladder, halting the development of urinary tract infections (UTIs) in mice. Since the new compounds do not destroy microbes or block their replication — as traditional antibiotics do — the researchers anticipate that bacteria responsible for most UTIs would have a harder time evolving resistance to them.

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